首页   按字顺浏览 期刊浏览 卷期浏览 Use of a molecular probe for detecting JCV DNA directly in human brain material
Use of a molecular probe for detecting JCV DNA directly in human brain material

 

作者: P. E. Gibson,   S. D. Gardner,   A. M. Field,  

 

期刊: Journal of Medical Virology  （WILEY Available online 1986）
卷期: Volume 18, issue 1  

页码: 87-95

 

ISSN:0146-6615

 

年代: 1986

 

DOI:10.1002/jmv.1890180111

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

关键词: progressive multifocal leucoencephalopathy;hybridot;JC virus DNA

 

数据来源: WILEY

 

摘要:

AbstractA hybridot assay using a radiolabelled JC virus probe has been used to detect the presence of JCV DNA in brain biopsy and postmortem brain samples from patients with neurological disease and possible progressive multifocal leucoencephalopathy. Sixty‐nine brain samples from 45 patients were examined. Eleven samples from eight patients had detectable JCV DNA sequences. In seven of the eight patients this result was confirmed by electron microscopy and/or virus isolation or immunofluorescenc

 

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