Enzymzytochemische und immunzytologische Differenzierung von Infiltratzellen in der Haut bei Mycosis fungoides
作者:
Stanislaus A. Büchner,
期刊:
Dermatology
(Karger Available online 1979)
卷期:
Volume 159,
issue 5
页码: 386-392
ISSN:1018-8665
年代: 1979
DOI:10.1159/000250645
出版商: S. Karger AG
关键词: Acid esterase;Acid phosphatase;Cytochemistry;T-lymphocytes;Mycosis fungoides
数据来源: Karger
摘要:
In 4 patients with mycosis fungoides in the praemycotic, infiltrative and tumour stage of the disease, a differentiation and functional characterization of the infiltrate cells, obtained from cell suspensions and cutaneous smears, was carried out by means of enzyme cytochemical and immunological methods. The lymphocyte-associated acid esterase is considered to be a marker for mature T-cell populations. Apart from monocytes and histiocytes, acid esterase-positive small lymphocytoid cells with T-cell properties are found in the praemycotic stage. In the tumour stage, large lymphocytoid cells become increasingly prevalent, they show no acid esterase activity, but an intracytoplasmatic-localized reaction in the acid phosphatase activity. On the basis of the cytochemical pattern, it is assumed that these cells represent proliferating lymphoblasts.
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