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No association between serotonin 2A receptor gene variants and personality traits

 

作者: Erik G. Jönsson,   Markus M. Nöthen,   J. Petter Gustavsson,   Cecilia Berggård,   Roland Bunzel,   Kaj Forslund,   Gunnar Rylander,   Marja Mattila‐Evenden,   Peter Propping,   Marie Åsberg,   Göran Sedvall,  

 

期刊: Psychiatric Genetics  （OVID Available online 2001）
卷期: Volume 11, issue 1  

页码: 11-17

 

ISSN:0955-8829

 

年代: 2001

 

出版商: OVID

 

关键词: serotonin;5‐HT2A;genetics;association study;Karolinska Scales of Personality

 

数据来源: OVID

 

摘要:

Among theories of biological underpinnings to personality traits, different mechanisms of the serotonergic system are perhaps the most common factors suggested to influence individual differences in personality traits. We have investigated two frequent variants in the serotonin 2A receptor gene (5‐HT2A) and personality traits. Healthy Swedish subjects (n = 304) were assessed with the Karolinska Scales of Personality (KSP) inventory. After correction for multiple testing, no significant differences were found. We conclude that the investigated 5‐HT2Agene variants do not significantly influence personality as assessed by the KSP in the present population.

 

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