Chronic Ergotamine Abuse: Evidence of Functional Impairment of Long Ascending Spinal Tracts
作者:
A.C. Ludolph,
I.W. Husstedt,
H.-P. Schlake,
K.-H. Grotemeyer,
G.G. Brune,
期刊:
European Neurology
(Karger Available online 1988)
卷期:
Volume 28,
issue 6
页码: 311-316
ISSN:0014-3022
年代: 1988
DOI:10.1159/000116292
出版商: S. Karger AG
关键词: Ergotism;Neurotoxicology;Long spinal tracts
数据来源: Karger
摘要:
22 migraine patients with a history of chronic ergotamine abuse were compared with 12 patients with a similar intake of dihydroergotamine. The study of somatosensory-evoked potentials showed that 50% of the patients with a history of ergotamine abuse had increased central conduction times after stimulation of the tibial nerve. Corticomotoneuronal latencies obtained by noninvasive electrical stimulation of the motor cortex were normal in 5 patients. The functional sensory deficits were not related to clinical impairment and were more frequently observed in patients with a comparatively high mean daily and cumulative intake.
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