The present study was undertaken in order to determine the changes in blood levels of lipid peroxide and vitamin E in EPH gestosis. The mean plasma level of lipid peroxide was 0.89 ± 0.13 nmol/ml for nonpregnant women, while for normal pregnant women it was 2.51 ± 0.52 nmol/ml, and 4.10 ± 0.72 nmol/ ml for women with EPH gestosis. The mean plasma level of vitamin E was 6.7 ± 1.0 μg/ml for nonpregnant women, while for normal pregnant women it was 14.5 ± 2.2 μg/ml and 12.6 ± 1.2 μg/ml for women with gestosis. The mean red cell level of vitamin E was 3.55 ± 0.25 μg/ml packed red cells in nonpregnant women, while in normal pregnant women it was 2.56 ± 0.34 μg/ml packed cells and 2.90 ± 0.28 μg/ml packed cells for women with EPH gestosis. The mean platelet level of vitamin E was 99 ± 25 μg/g protein for nonpregnant women, while in normal pregnant women it was 232 ± 24 μg/g protein and 205 ± 32 μg/g protein for women with EPH gestosis. It was shown in this study that in EPH gestosis the plasma level of lipid peroxide increased while the levels of vitamin E which inhibited the formation of lipid peroxide decreased in plasma, red cells and platelets.