Pressure-Induced Ischemia
作者:
M. Romanus,
H. Haljamäe,
期刊:
European Surgical Research
(Karger Available online 1978)
卷期:
Volume 10,
issue 1
页码: 17-23
ISSN:0014-312X
年代: 1978
DOI:10.1159/000127988
出版商: S. Karger AG
关键词: Ischemia;Recirculation;Hamster cheek pouch;ATP;Glucose
数据来源: Karger
摘要:
The effects of pressure-induced ischemia on energy metabolism, measured as ATP and glucose content, is studied in hamster cheek pouch. Metabolic deterioration during ischemia is studied and after 2 h the glucose content was significantly reduced but not the ATP content, which was significantly reduced after 4 h of ischemia. Restoration of glucose levels in the cheek pouch tissue was achieved within 30 min of recirculation after release of pressure. The cellular energy metabolism is unable after 4 h of ischemia to restore ATP levels in the tissue during the 120-min of postischemic observation time. There is a difference in ability to resume normal energy metabolism after 2 and 4 h of pressure-induced ischemia.
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