A comparison of mouthrinses containing two concentrations of chlorhexidine
作者:
V. A. Segreto,
E. M. Collins,
B. B. Beiswanger,
M. Rosa,
R. L. Isaacs,
N. P. Lang,
M. E. Mallatt,
A. H. Meckel,
期刊:
Journal of Periodontal Research
(WILEY Available online 1986)
卷期:
Volume 21,
issue 1
页码: 23-32
ISSN:0022-3484
年代: 1986
DOI:10.1111/j.1600-0765.1986.tb01512.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
A 3‐month clinical trial was conducted to compare the effects of two concentrations of a chlorhexidine mouthrinse on gingivitis and plaque accumulation. Six hundred (600) adults were divided into three treatment groups matched for age, sex, and initial gingivitis severity. Following a thorough examination and prophylaxis at baseline, subjects were given a mouthrinse containing either 0.12% or 0.20% chlorhexidine gluconate or a placebo mouthrinse. Subjects were evaluated after 6 weeks and 3 months of mouthrinse use. After 3 months, both chlorhexidine groups showed significantly less gingivitis and plaque than the placebo group. The group using the 0.12% chlorhexidine gluconate mouthrinse demonstrated 27–27 % less gingivitis occurrence and 28–28% less gingivitis severity than the placebo group. The 0.12% chlorhexidine gluconate group also had 48–48% less gingival bleeding and 36% less plaque than the placebo group. There were no significant advantages for the 0.20% mouthrinse over the 0.12% mouthrinse. It is therefore concluded that a 0.12% chlorhexidine gluconate mouthrinse offers the same clinical benefits as a 0.20% chlorhexidine gluconate mou
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