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A study of biocides for the selection of candidates for carcinogen bioassay

 

作者: O.H. Johnson,   S. Casey,   M.K. Doeltz,   K.E. McCaleb,   A.M. Miller,   P.A. Papa,   L.B. Swett,   M.A. Valentini,   C.T. Helmes,  

 

期刊: Journal of Environmental Science and Health . Part A: Environmental Science and Engineering  (Taylor Available online 1984)
卷期: Volume 19, issue 1  

页码: 1-25

 

ISSN:0360-1226

 

年代: 1984

 

DOI:10.1080/10934528409375146

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

The use class of biocides was studied in order to nominate chemicals as candidates for carcinogen bioassay to the National Cancer Institute. After the application of several qualifying criteria that related to previous, current, or planned carcinogenicity testing and to commercial significance, the preliminary candidate list of 295 chemicals was reduced to a list of 61 final candidate chemicals. Based upon consideration of both the suspicion of possible carcinogenic activity and evidence indicating potential human exposure, the following eight chemicals were nominated: benzethonium chloride, hexahydro‐1,3,5‐tris(2‐hydroxy‐ethyl)triazine, benzyldimethyl(mixed alkyl)ammonium chloride, N‐(3‐chloroallyl)hexaminium chloride, 2,4,5‐trichlorophenol, o‐benzyl‐p‐chlorophenol, l,2‐benzisothiazolin‐3‐one, and zinc pyrithione.

 

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