Hypercalcemia in Patients with Advanced Chronic Renal Failure Not Yet Requiring Dialysis
作者:
Arthur Greenberg,
Beth M. Piraino,
Frank J. Bruns,
期刊:
American Journal of Nephrology
(Karger Available online 1989)
卷期:
Volume 9,
issue 3
页码: 205-210
ISSN:0250-8095
年代: 1989
DOI:10.1159/000167966
出版商: S. Karger AG
关键词: Hypercalcemia;Tertiary hyperparathyroidism;Aplastic bone;Chronic renal failure
数据来源: Karger
摘要:
Six patients with progressive chronic renal failure not yet requiring dialysis and not consuming supplemental calcium or vitamin D developed hypercalcemia. Three had proven and 1 suspected tertiary hyperparathyroidism, 1 parathyroid carcinoma and 1 aplastic bone. None of the 3 patients who underwent bone biopsy had heavy bone aluminum staining. The patients with proven parathyroid-mediated hypercalcemia had marked elevation of C-terminal parathyroid hormone and alkaline phosphatase values and, when performed, radiographs consistent with osteitis fibrosa. When these findings are absent or the diagnosis is otherwise uncertain, a bone biopsy may provide a definitive diagnosis and guide management.
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