Nephrogenic Diabetes insipidus Presenting after Head Trauma
作者:
Hariprasad S. Trivedi,
Karl D. Nolph,
期刊:
American Journal of Nephrology
(Karger Available online 1994)
卷期:
Volume 14,
issue 2
页码: 145-147
ISSN:0250-8095
年代: 1994
DOI:10.1159/000168704
出版商: S. Karger AG
关键词: Head trauma;Lithium;Nephrogenic diabetes insipidus
数据来源: Karger
摘要:
Water diuresis after head trauma is most often due to central diabetes insipidus (DI). We report a patient with a history of a bipolar disorder and past lithium use who was noted to have polyuria and hypernatremia after head trauma. Inappropriate high sodium and volume replacement resulted in an increase in the polyuria. A lack of response to antidiuretic hormone/antidiuretic-hormone-like preparations led to the diagnosis of nephrogenic DI. The case illustrates the importance of calculating electrolyte-free osmolar clearance in the correction of hypernatremia. Persistence of the DI and mild renal impairment probably due to past lithium use are discussed.
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