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Assignment of the human gene for the water channel of renal collecting duct Aquaporin 2 (AQP2) to chromosome 12 region q12→q13

 

作者: P.M.T. Deen,   D.O. Weghuis,   R.J. Sinke,   A. Geurts van Kessel,   B. Wieringa,   C.H. van Os,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1994）
卷期: Volume 66, issue 4  

页码: 260-262

 

ISSN:1424-8581

 

年代: 1994

 

DOI:10.1159/000133707

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

The chromosomal localization of the gene encoding Aquaporin 2 (previously called WCH-CD), which acts as a water channel in the collecting tubules of the kidney, was determined. Southern blot hybridizations of chromosomal DNA from a panel of 25 different human-rodent hybrid cell lines assigned AQP2 to the q-arm of human chromosome 12. Additionally, in situ hybridization on R-banded metaphase chromosomes localized AQP2 to the q12→q13 region of this chromosom

 

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