Cardiovascular Effects of Oxytocin
作者:
F ROBERT WEIS,
ROSS MARKELLO,
BENJAMIN MO,
PASQUALE BOCHIECHIO,
期刊:
Obstetrics & Gynecology
(OVID Available online 1975)
卷期:
Volume 46,
issue 2
页码: 211-214
ISSN:0029-7844
年代: 1975
出版商: OVID
数据来源: OVID
摘要:
Oxytocin, 5 to 10 units, is frequently given as a bolus injection following terra delivery or elective termination of pregnancy. It is not general knowledge that this has any untoward effects. In the present study in young, healthy women undergoing elective termination of pregnancy, mean arterial blood pressure decreased approximately 30% and the total peripheral resistence 50%, 40 seconds after injection. However, heart rate increased 30% and stroke volume 25%, so that the cardiac output was elevated more than 50% above control. Oxytocin given as a dilute solution produced no circulatory change; hence, we suggest that this drug be administered in such fashion rather than by bolus injection.
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