Pancreatic and Catalytic Phospholipase A2in Relation to Pregnancy, Labor and Fetal Outcome
作者:
M.O. Pulkkinen,
J. Eskola,
V. Kleimola,
N.H. Simberg,
T. Thuren,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1990)
卷期:
Volume 29,
issue 2
页码: 104-107
ISSN:0378-7346
年代: 1990
DOI:10.1159/000293312
出版商: S. Karger AG
关键词: Phospholipase;Pancreas;Pregnancy;Postmaturity;Pruritus;Umbilical cord blood;Fetal distress
数据来源: Karger
摘要:
The serum pancreatic and catalytic phospholipase A2 level (PLA2) in human pregnancy is normal, and the increase of pancreatic enzyme before delivery is small. In patients with pruritus associated with obstetric hepatosis maternal serum had a slightly lower pancreatic PLA2 level if the cholic acid level was higher. Umbilical cord blood has twice as much pancreatic PLA2 as maternal blood. If the enzyme concentration was very high, pregnancies were postterm and the newborns had low Apgar scores. Amniotic fluid contains these enzymes, but there is no change in the enzymes during the course of pregnancy. The amount of pancreatic enzyme was not reflected in catalytic activity. A very high PLA2 activity was observed in 1 patient with suspected amniotic fluid embolism and in the meconium, but low in the first urine of neonates.
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