Asymptomatic Low Molecular Weight Proteinuria: Qualitative Urinary Protein Analysis
作者:
Takeshi Watanabe,
Shori Takahashi,
期刊:
Pediatrics International
(WILEY Available online 1992)
卷期:
Volume 34,
issue 1
页码: 28-35
ISSN:1328-8067
年代: 1992
DOI:10.1111/j.1442-200X.1992.tb00921.x
出版商: Blackwell Publishing Ltd
关键词: Asymptomatic low molecular weight proteinuria;Electrophoresis;Renal tubular diseases.
数据来源: WILEY
摘要:
The urinary proteins of seven patients with asymptomatic low molecular weight proteinuria (ALMP) were compared with those of Lowe syndrome and Fanconi syndrome. A characteristic electrophoretic pattern was seen in ALMP by isoelectric focusing. Two dimensional electrophoresis revealed that the ALMP proteins were localized in a more negatively charged region of lower molecular weight and consisted of a smaller variety of proteins in comparison with those from Fanconi syndrome and Lowe syndrome. These results suggest that ALMP might be an isolated form of other types of congenital renal tubular diseases from the viewpoint of protein reabsorption and has a lesser functional defect on the proximal tubules.
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