The influence of pentoxifylline on motility and viability of spermatozoa from normozoospermic semen samples
作者:
HERMAN TOURNAYE,
RONNY JANSSENS,
PAUL DEVROEY,
ANDRK STEIRTEGHEM,
期刊:
International Journal of Andrology
(WILEY Available online 1994)
卷期:
Volume 17,
issue 1
页码: 1-8
ISSN:0105-6263
年代: 1994
DOI:10.1111/j.1365-2605.1994.tb01200.x
出版商: Blackwell Publishing Ltd
关键词: CASA;computer‐assisted semen analysis;methylxanthines;motility longevity;pentoxifylline;sperm motility;sperm survival
数据来源: WILEY
摘要:
SummaryIn order to evaluate the effects of pentoxifylline on sperm motility and longevity, a controlled in‐vitro study was conducted on normozoospermic donor semen samples using the Cellsoft automated system for sperm motility analysis. After incubation and selection, pentoxifylline was found to improve the recovery of spermatozoa and to increase their velocity. In the subgroup of progressively motile spermatozoa, curvilinear velocity was also enhanced. It is concluded that pentoxifylline has an effect on the vigour, but not on the pattern, of sperm motion. Pentoxifylline did not improve the motility characteristics of senescent spermatozoa in normozoospermic sperm samples. Sperm survival, as shown by supra‐vital staining, and motility longevity both decreased with time after pentoxifylline treatm
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