Maternal Hemodynamic Adjustments in Idiopathic Fetal Growth Retardation
作者:
P. Rosso,
E. Donoso,
S. Braun,
R. Espinoza,
C. Fernandez,
S.P. Salas,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1993)
卷期:
Volume 35,
issue 3
页码: 162-165
ISSN:0378-7346
年代: 1993
DOI:10.1159/000292690
出版商: S. Karger AG
关键词: Plasma volume;Cardiac output;Pregnancy;Fetal growth retardation;Total peripheral vascular resistance
数据来源: Karger
摘要:
The hemodynamic characteristics of 11 normotensive gravidas with idiopathic fetal growth retardation (FGR), were compared with 11 controls of similar age, parity and body size. At weeks 36–38 of gestation, plasma volume was 3,161 ± 121 ml in controls and 2,624 ± 95 ml in the FGR group (p < 0.003); cardiac output (CO) was 6,191 ± 132 ml/min in controls and 5,483 ± 186 ml/min in the FGR group (p < 0.01). Total peripheral vascular resistance (TPVR) was lower in controls than in FGR (1,031 ± 33 vs. 1,306 ± 62 dyn/s/cm5; p < 0.001). Birth weight was correlated with both plasma volume (r = 0.61; p < 0.01) and CO (r = 0.53; p < 0.02) and inversely correlated with TPVR (r = ––0.69; p < 0.001). These results are in line with the hypothesis that a reduced plasma volume leads to a lower CO and, secondarily, to reduced uterine blood flow and FGR.
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