Segregation Analysis of the NIMH Collaborative Study. Family Data on Bipolar Disorder
作者:
Pak Sham,
Newton Morton,
John Rice,
期刊:
Psychiatric Genetics
(OVID Available online 1992)
卷期:
Volume 2,
issue 3
页码: 175-184
ISSN:0955-8829
年代: 1992
出版商: OVID
数据来源: OVID
摘要:
Expanded analyses of the NIMH Collaborative Study family data on bipolar disorder showed that an earlier suggestion of non-Mendelian transmission was dependent on the definition of the liability indicator. When an appropriate liability indicator was used. polygenic and generalised single major locus models were almost equally compatible with the data.
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