ABSTRACTOur immense national water quality control program has been launched on a wholly empirical basis, much as our ancestors initiated early navigation improvements and flood control. Not only has there been no effort to determine the benefits of water quality control; the theoretical groundwork for optimization has not been developed. Three main national objectives for consideration are national economic efficiency, preserving and improving the national environment for man's use and development (conservation), and regional development. Although popular at present, the regional development objective is not particularly useful from an economic viewpoint. Efficiency objectives other than environmental can be evaluated but are apt to be minor. Other water quality benefits can be broken down appropriately into four main categories: (a) man's recreational environment; (b) man's home environment; (c) man's working environment; (d) intangibles related to scientific, historic, health and cultural values. In management of water quality, various technical relationships must be considered, particularly as to quantity of water needed for waste disposal, and relationship of this use to water supply withdrawals. Advanced waste treatment must be compared with other alternatives, not only of flow augmentation, but also technological process changes, distribution of effluents, and artificial river aeration.