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Pneumococcal polysaccharide immunization of children with sickle cell disease. I. Clinical reactions to immunization and relationship to preimmunization antibody

 

作者: Gary Overturf,   Darleen Powars,   Joyce Weiss,   Jose Rigau-Perez,   Emily Pang,   Linda Chan,   Jeffrey Selzer,   Corazon Uy,   Bernard Portnoy,   Ronald Field,   George Honig,  

 

期刊: American Journal of Pediatric Hematology/Oncology  （OVID Available online 1982）
卷期: Volume 4, issue 1  

页码: 19-24

 

ISSN:0192-8562

 

年代: 1982

 

出版商: OVID

 

数据来源: OVID

 

摘要:

Vaccine reaction data were obtained from 154 patients with sickle cell disease immunized with tetradecavalent pneumococcal polysaccharide vaccine. There was a high rate (70%) of mild reactions, primarily at the site of injection. Fever over 100°F was uncommon and precipitation of symptoms similar to sickling crisis was rare. Development of local reactions was associated with the level of preimmunization pneumococcal antibody titer.

 



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