The Use of Complement Fixation Tests to Detect Australia Antigen‐Antibody Complexes and Antibodies to a Tween Antigen1
作者:
L. Thiry,
G. Clinet,
C. Toussainty,
P. Vereerstraeten,
期刊:
Vox Sanguinis
(WILEY Available online 1973)
卷期:
Volume 24,
issue 1
页码: 36-43
ISSN:0042-9007
年代: 1973
DOI:10.1111/j.1423-0410.1973.tb03511.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Abstract.Indications were obtained that Australia antigen‐antibody complexes are more frequent in patients with cirrhosis than in other Australia antigen‐positive individuals. The evidences were: (1) Among sera with high titres of Australia antigen, anticomplementary activity was detected at lower dilutions in 53% of the cases of cirrhosis, as compared to 14 and 7% in hepatitis patients and carriers, respectively. (2) Among anticomplementary sera which did not show Australia antigen at higher dilutions, the antigen was unmasked after heating at 85 °C in 4 of 7 cases of cirrhosis and in 2 of 11 other patients.On the other hand, a new type of antibody was demonstrated in three patients who had experienced a progressive decrease of Australia antigen titre; the antibodies were detected after the disappearance of the antigen, but they reacted only with some antigenic component of Australia‐positive sera which was unmasked after treatment with Tw
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