Interpretation Criteria for Sensitivity Testing of Ceftriaxone in Agar Diffusion Test according to the DIN 58940 Method
作者:
H. Grimm,
期刊:
Chemotherapy
(Karger Available online 1984)
卷期:
Volume 30,
issue 1
页码: 49-53
ISSN:0009-3157
年代: 1984
DOI:10.1159/000238245
出版商: S. Karger AG
关键词: Ceftriaxone;Microbiology;Minimal inhibitory concentration;Inhibitory zone
数据来源: Karger
摘要:
On the basis of a regression analysis of the correlation between minimal inhibitory concentration (MIC) and inhibitory zone diameter, interpretative criteria are established for the agar diffusion test with ceftriaxone disks (30 μg) in DST agar according to the DIN method. The correlation is good (r = -0.9242); the regression equation is x = -0.43 y + 20.53 (y = inhibitory zone diameter, x = log2MIC + 9). Following appropriate discussion, provisional MIC breakpoints of 8 and 32 mg/l are proposed for ceftriaxone. On the basis of these threshold values, the following criteria are established for interpreting the inhibition zone of ceftriaxone: resistance (corresponding to an MIC of 64 mg/l and more up to 15 mm; moderate sensitivity (corresponding to an MIC of 16–32 mg/l) 16–19 mm; sensitivity (corresponding to an MIC of up to 8 mg/l) 20 mm and
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