Research on the affects of wine programs in geriatric units and nursing homes, as well as among elderly living in the community, has demonstrated that moderate use of wine in later life is beneficial. Benefits noted in these studies include improved morale, more zest for life, more mature social interaction, more restful sleep at night, and reduction in the use of psychotropic drugs. Of particular note were improved relations between patients and staff in nursing homes. This was attributable to the increased self-esteem of the patients who became more interesting as human beings to the staff. A psychosocial explanation of these changes centers on wine as a symbol of maturity and conviviality, allowing the old person to feel once again grown-up and part of the human family. Our psychobiological hypothesis is that chronic fatigue may be responsible for some of the behaviours associated with old age. Poor sleep may be attributable to a deficit of fama-amino-butyric acid (GABA), a substance found in the body as it prepares for sleep and also in wine. Although our behavioral data point to the positive effects of wine on sleep and related psychosocial behaviors, more research is required. To promote moderate use of wine among the elderly, attention should be given to educating them about the value of wine. The wine industry could also develop wines which would be especially appealing to older people.