Tear Function Parameters in Keratoconjunctivitis sicca with and without the Association of Sjögren's Syndrome
作者:
A.J. Mackor,
O.P. van Bijsterveld,
期刊:
Ophthalmologica
(Karger Available online 1988)
卷期:
Volume 196,
issue 4
页码: 169-174
ISSN:0030-3755
年代: 1988
DOI:10.1159/000309895
出版商: S. Karger AG
关键词: Keratoconjunctivitis sicca;Sjögren’s syndrome;Lysozyme;Lactoferrin;Schirmer I test;Break-up time;Rose bengal score
数据来源: Karger
摘要:
In a group of patients with keratoconjunctivitis sicca (KCS) associated with Sjögren’s syndrome (SJ) a significant decrease in tear fluid lactoferrin concentration and tear film break-up time was demonstrated in comparison with a matched group in which KCS was not associated with any systemic disease. The Schirmer values were also lower in the SJ of patients and these differences almost reached statistical significance. None of these parameters in itself appeared to be of any clinical value to differentiate between KCS that was or was not associated with SJ. The combination of the tear fluid lactoferrin concentration, the Schirmer I test values and the tear film break-up time, however, provide a basis for differential diagnosis that is clinically of some value.
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