Interferons in the Therapy of Solid Tumors
作者:
Sanjiv S. Agarwala,
John M. Kirkwood,
期刊:
Oncology
(Karger Available online 1994)
卷期:
Volume 51,
issue 2
页码: 129-136
ISSN:0030-2414
年代: 1994
DOI:10.1159/000227327
出版商: S. Karger AG
关键词: Interferons;Therapy;Tumors;Melanoma;Review;Systemic;Immunotherapy;Chemotherapy
数据来源: Karger
摘要:
Interferons, a group of naturally occurring proteins, possess potent immunological effects. The availability of large amounts of purified interferon through recombinant DNA technology has led to the testing of these agents against a number of tumor types. Interferon-α has been the most widely studied. The most encouraging results have been observed in the treatment of melanoma among nonhematological neoplasms, and in the locoregional treatment of other tumor types. It is hoped that further research into the use of the interferons, both singly and in combination with chemotherapy and other immunological agents, will lead to a better elucidation of their therapeutic role against cancer. In this article, the use of interferons in the treatment of solid tumors is reviewed
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