Incidence and Diagnosis of EDTA‐Dependent Pseudothrombocytopenia in a Consecutive Outpatient Population Referred for Isolated Thrombocytopenia
作者:
Federico Silvestri,
Luigi Virgolini,
Chiara Savignano,
Francesco Zaja,
Marinella Velisig,
Michele Baccarani,
期刊:
Vox Sanguinis
(WILEY Available online 1995)
卷期:
Volume 68,
issue 1
页码: 35-39
ISSN:0042-9007
年代: 1995
DOI:10.1111/j.1423-0410.1995.tb02542.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
AbstractAmong 111 patients referred to our outpatient clinic for isolated thrombocytopenia during a 24‐month period, 17 (15.3%) cases of EDTA‐dependent pseudothrombocytopenia (EDTA‐PTCP) were identified. EDTA‐PTCP represented the second most frequent cause of thrombocytopenia in this population. The diagnosis was confirmed by the following findings: (a) normal platelet numbers immediately after blood withdrawal; (b) progressive fall of platelet counts and evident platelet clumping over time, only in EDTA‐anticoagulated blood. A simple, inexpensive and quick diagnostic method was devised, that consists in evaluating the platelet number in a blood sample anticoagulated with EDTA immediately after blood withdrawl and
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