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Association between Indicators of Perinatal Asphyxia and Adverse Outcome in the Term Infant: A Methodological Review

 

作者: Robert L. Bryce,   Mary E. Halperin,   John C. Sinclair,  

 

期刊: Neuroepidemiology  (Karger Available online 1985)
卷期: Volume 4, issue 1  

页码: 24-38

 

ISSN:0251-5350

 

年代: 1985

 

DOI:10.1159/000110211

 

出版商: S. Karger AG

 

关键词: Asphyxia neonatorum;review;Asphyxia;risk and seizures;Cerebral palsy;Follow-up studies;Infant mortality;Infant;newborn;Mental retardation;Nervous system diseases

 

数据来源: Karger

 

摘要:

There are conflicting opinions about the significance of 5 perinatal findings felt to be indicators of asphyxia (meconium staining of the amniotic fluid, abnormal fetal heart rate patterns, acidotic fetal scalp blood gases, low Apgar scores, and acidotic cord blood gases). A review of the literature was undertaken to determine the strength of association of each of these findings with adverse outcomes. Although all studies contained methodological problems, these indicators were found to have strong associations with one or more adverse outcomes such as perinatal death, low Apgar scores or cerebral palsy. The strength of the association (relative risk) was found to vary inversely with the prevalence of the outcome.

 

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