This report describes a patient with unusual ophthalmologic complications of Graves' disease. At the age of 56, the patient developed retinal vein thrombosis, and one year later optic atrophy of the other eye. Subsequently he developed the more commonly described signs of Graves' ophthalmopathy, including exophthalmos, stare, lid lag, and chemosis. The findings in this patient suggest that retinal vein thrombosis may occur in Graves' disease, and that optic neuritis may develop in the absence of more obvious signs of ophthalmopathy.