Response to Immunosuppressive Therapy in Patients with Hereditary Motor and Sensory Neuropathy and Associated Dysimmune Neuromuscular Disorders
作者:
Galen W. Mitchell,
E. Peter Bosch,
Michael N. Hart,
期刊:
European Neurology
(Karger Available online 1987)
卷期:
Volume 27,
issue 3
页码: 188-196
ISSN:0014-3022
年代: 1987
DOI:10.1159/000116154
出版商: S. Karger AG
关键词: Hereditary motor and sensory neuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;Polymyositis;Immunosuppressive therapy
数据来源: Karger
摘要:
We encountered 2 patients with hereditary motor and sensory neuropathy (HMSN) type I who had marked weakness developing during several months superimposed on chronic peroneal muscular atrophy. Further studies disclosed a chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in one patient and CIDP associated with polymyositis in the other. Both patients responded to prednisone and azathioprine with substantial improvement. Patients with HMSN who develop rapid progression of weakness should be evaluated for superimposed, potentially treatable dysimmune neuromuscular disorders.
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