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Assessing the Treatment of Solar Urticaria

 

作者: Patricia Michell,   J.L.M. Hawk,   A. Shafrir,   Margaret F. Corbett,   I.A. Magnus,  

 

期刊: Dermatology  （Karger Available online 1980）
卷期: Volume 160, issue 3  

页码: 198-207

 

ISSN:1018-8665

 

年代: 1980

 

DOI:10.1159/000250495

 

出版商: S. Karger AG

 

关键词: Solar urticaria;Weal;Antihistamine H1and H2;Chlorpheniramine;Cimetidine;Dose-response curves

 

数据来源: Karger

 

摘要:

The weal and flare produced by monochromatic irradiation in solar urticaria may be treated as a classical dose-response. This has been used to investigate therapy with H1 and H2 antihistamines. The conventional H1 drug proved superior. But from the practical viewpoint, solar urticaria is difficult to suppress even with a relatively efficient H1 antihistamine, chlorpheniramine; the mean protective factor in 5 patients was only 2, insufficient for satisfactory clinical management.

 

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