TOLERANCE AND THE H‐Y ANTIGENREQUIREMENT FOR MALE T CELLS, BUT NOT B CELLS, TO INDUCE TOLERANCE IN NEONATAL FEMALE MICE
作者:
IRVING WEISSMAN,
LIBUSE JERABEK,
SUSAN GREENSPAN,
期刊:
Transplantation
(OVID Available online 1984)
卷期:
Volume 37,
issue 1
页码: 3-6
ISSN:0041-1337
年代: 1984
出版商: OVID
数据来源: OVID
摘要:
Transplantation tolerance of the H-Y antigen may be induced and transferred by lymphoid cells, but not by nonlymphoid cells. In this study we have demonstrated that amongst lymphoid cells, T cells—but not B cells or macrophages—are capable of inducing transplantation tolerance. In contrast, all three populations express sufficient amounts of immunogenic H-Y antigen to sensitize adult female mice to a subsequent male skin graft, as demonstrated by the second-set reaction.
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