Rather than attempting to cover a wide range of statistical problems. I shall concentrate on four topics: 1) The argument between Bayesians and Frequentists, 2) A paradox in comparing data with two hypotheses; 3) The CLs method used in the search for the Higgs at CERN, 4) The MLBZ method of using data to estimate some of the systematic effects in measuring the W boson’s mass. ©2001 American Institute of Physics.