首页   按字顺浏览 期刊浏览 卷期浏览 Orosomucoid and Haptoglobin Excretion in Rat Glomerulonephritis and Tubulonephritis
Orosomucoid and Haptoglobin Excretion in Rat Glomerulonephritis and Tubulonephritis

 

作者: Françoise Pironneau,   Michel Sternberg,   Monique Moisy,   Jacques Feret,   Pierre Rebeyrotte,   Gilbert Lagrue,   Max-Fernand Jayle,  

 

期刊: Nephron  （Karger Available online 1974）
卷期: Volume 13, issue 6  

页码: 434-442

 

ISSN:1660-8151

 

年代: 1974

 

DOI:10.1159/000180422

 

出版商: S. Karger AG

 

关键词: Rat glomerulonephritis;Mercury;Tubulonephritis;Haptoglobin;Orosomucoid;Seromucoid

 

数据来源: Karger

 

摘要:

Haptoglobin and orosomucoid were detected and measured in concentrated normal rat urine by radial immunodiffusion. Normal haptoglobin clearance was 33 nl/min (190 nl/ min/kg) and normal orosomucoid clearance 146 nl/min (840 nl/ min/kg). During nephrotoxic serum glomerulonephritis both glycoproteins increased considerably in urine in two phases; in serum, after an early peak, haptoglobin returned to the normal level and orosomucoid fell below the normal value. During mercuric chloride tubulonephritis, an early sharp peak of both glycoproteins was observed chiefly in urine but also in serum.

 

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