Transient Anterior Horn Cell Dysfunction in Diphenylhydantoin Therapy
作者:
M. Direkze,
P.S.L. Fernando,
期刊:
European Neurology
(Karger Available online 1977)
卷期:
Volume 15,
issue 3
页码: 131-134
ISSN:0014-3022
年代: 1977
DOI:10.1159/000114801
出版商: S. Karger AG
关键词: Anterior horn cell;Fasciculations;Diphenylhydantoin therapy;Reversible motor neurone disease
数据来源: Karger
摘要:
A report on a patient who developed profuse fasciculations following diphenylhydantoin therapy for 30 months with subsequent complete recovery on cessation of therapy is presented. In view of the considerable variability of spontaneous potentials generated in spinal motor neurones, in vitro studies and pathological states with respect to shape, amplitude, frequency and duration, caution is advised in the assessment of the clinical significance of fasciculations. The possibility that our patient represents an instance of a ‘reversible form of motor neuron disease’ is entertai
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