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Beta-Adrenergic Receptors on Lymphoblasts

 

作者: Wade H. Berrettini,   Charles B. Cappellari,   John I. Nurnberger, Jr.,   Elliot S. Gershon,  

 

期刊: Neuropsychobiology  （Karger Available online 1987）
卷期: Volume 17, issue 1-2  

页码: 15-18

 

ISSN:0302-282X

 

年代: 1987

 

DOI:10.1159/000118334

 

出版商: S. Karger AG

 

关键词: Beta-adrenergic receptors;Manic-depressive illness;Lymphoblasts

 

数据来源: Karger

 

摘要:

Beta-adrenergic receptor function has been the subject of much research in manic-depressive illness. Lymphoblast beta receptor binding was analyzed by Scatchard plot, using cell lines established from 17 unrelated bipolar subjects and 14 normals. No significant differences in affinity or density of beta receptors were found, in contrast to a previous report. Both the affinity and density of receptors appeared to be a stable characteristic of a cell line, as determined by repeated assay of the same cell lines.

 

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