Immunological factors in milk from Brazilian mothers delivering small‐for‐date term neonates
作者:
AS Grumach,
RC Carmona,
D Lazarotti,
MA Ribeiro,
RB Rozentraub,
ML Racz,
A Weinberg,
MMS Carneiro‐Sampaio,
期刊:
Acta Pædiatrica
(WILEY Available online 1993)
卷期:
Volume 82,
issue 3
页码: 284-290
ISSN:0803-5253
年代: 1993
DOI:10.1111/j.1651-2227.1993.tb12661.x
出版商: Blackwell Publishing Ltd
关键词: Human milk analysis;immunology of human milk;infant nutrition;low‐birth‐weight newborns;viral antibodies
数据来源: WILEY
摘要:
Breast milk samples from three groups of Brazilian women were evaluated: G1, mothers delivering term babies of low birth weight (n=16); G2, mothers delivering preterm babies of appropriate birth weight (n = 20); G3, mothers delivering term babies of appropriate birth weight (n =30). Milk samples were obtained at 48 h and on the 7th, 15th, 30th and 60th days after delivery and they were analyzed for lysozyme and total IgA levels and for the presence of specific antibodies against Poliovirus types I, II, III, Rotavirus, Herpes simplex virus, Varicella zoster and Cytomegalovirus. The groups were not statistically different in relation to mother's age, parity, type of delivery or socio‐economic levels. IgA levels were higher in both low‐birth‐weight groups (G1&G2) compared to the control group (G3) throughout the study period. Lysozyme levels decreased up to the 15th day, increasing thereafter up to the 60th day in all groups. Specific antibodies were detected throughout the study period, with no differences among groups. We conclude that breast milk composition of mothers delivering low‐birth‐weight babies (G1&G2) was similar despite the different gestati
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