Effects of anesthetics on sulfate transport in the red cell
作者:
Alexandros Makriyannis,
Stephen W. Fesik,
期刊:
Journal of Neuroscience Research
(WILEY Available online 1980)
卷期:
Volume 5,
issue 1
页码: 25-33
ISSN:0360-4012
年代: 1980
DOI:10.1002/jnr.490050105
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: anesthetics;steroids;anion;transport
数据来源: WILEY
摘要:
AbstractWe have measured the effect of anesthetics on sulfate transport in the human erythrocyte and have found that a wide variety of chemical classes of anesthetics, including the anesthetic steroid alphaxalone, inhibit sulfate transport in human erythrocytes at concentrations paralleling the concentrations that block nerve conduction. These experiments suggest that anesthetics act through a general mechanism and that the sulfate transport system in the red blood cell is a good model for studying the mechanism of action of anesthetics.
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