The aim of the present scanning electron microscopy study was to document the nature of morphologic changes occurring in human enamel and dentin subjectedin vitroto temperatures in the range of 200–1,000 °C for variable times. The results of the investigation confirm that human enamel and dentin remain microscopically identifiable after incineration at 1000 °C.Furthermore, these tissues ramain identifiable afterincineration at 1,000 °C for periods greater than 3h.No consistent or reliable differences in morphology could be detected in enamel or mineralized dentin incinerated in the temperature range 200–600 °C. Temperature-dependent changes involving the predentin zone were observed. Folloing incineration at 800 °C for over 3 h and at 1,000°C for 3 form was observed.