Ocular Blood Flow in Experimental Glaucoma: A Study in Cynomolgus Monkeys
作者:
Albert Alm,
George N. Lambrou,
Olav Mäepea,
Siv F.E. Nilsson,
Christine Percicot,
期刊:
Ophthalmologica
(Karger Available online 1997)
卷期:
Volume 211,
issue 3
页码: 178-182
ISSN:0030-3755
年代: 1997
DOI:10.1159/000310786
出版商: S. Karger AG
关键词: Ocular blood flow;Experimental glaucoma;Labeled microspheres
数据来源: Karger
摘要:
Experimental glaucoma was induced in 1 eye of 6 cynomolgus monkeys by laser treatment of the trabecular meshwork. In 5 of the 6 monkeys the increased intraocular pressure (IOP) caused marked glaucomatous damage in the experimental eye. Ocular blood flow was determined with labeled microspheres 4 years after the laser treatment. IOP was regulated with an external reservoir. With the same perfusion pressure in both eyes no statistically significant difference was observed between the 2 eyes for total ocular blood flow or for blood flow through any of the ocular tissues. Total ocular blood flow was 343.5+61.4 mg/min (mean ± SEM) in the control eye and 385.3 ± 107.7 mg/min in the experimental ey
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