The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study.
作者:
LondonR S,
SundaramG S,
MurphyL,
GoldsteinP J,
期刊:
Journal of the American College of Nutrition
(Taylor Available online 1983)
卷期:
Volume 2,
issue 2
页码: 115-122
ISSN:0731-5724
年代: 1983
DOI:10.1080/07315724.1983.10719916
出版商: Routledge
数据来源: Taylor
摘要:
In a double-blind, randomized dose-response study, 75 women with benign breast disease were administered a written questionnaire in which they scored the severity of premenstrual syndrome (PMS) symptoms before and after two months of treatment with placebo or alpha-tocopherol (150, 300, or 600 IU/day). Controlling for age and pretreatment scores, alpha-tocopherol had a significantly greater effect than placebo, improving three of the four classes of PMS symptoms. These findings suggest that vitamin E supplementation may be of value in women with severe PMS symptoms.
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