Typing for RhLA‐D in rhesus monkeys: II. Genetics of the D antigens and their association with DR antigens in a population of unrelated animals1
作者:
M. Jonker,
G. Van Meurs,
H. Balner,
期刊:
Tissue Antigens
(WILEY Available online 1982)
卷期:
Volume 19,
issue 1
页码: 69-78
ISSN:0001-2815
年代: 1982
DOI:10.1111/j.1399-0039.1982.tb01417.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
A population of 94 unrelated rhesus monkeys was typed for MLC antigens using 38 homozygous typing cells which define ten RhLA—D specificities. A genetic analysis showed that the ten D specificities are alleles of a single locus, the gene frequencies of which are in Hardy‐Weinberg equilibrium. The association between the cellularly defined D and the serologically defined DR antigens in the population was usually high, confirming the close relationship between D and DR antigens. Two new associations were found, i.e. between the D‐locus antigens 9 and 10 and the serologically defined B‐cell antigens 109 and 101, respectively. This observation confirms prior speculations that the latter two antigens may belong to the DR
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