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Typing for RhLA‐D in rhesus monkeys: II. Genetics of the D antigens and their association with DR antigens in a population of unrelated animals1

 

作者: M. Jonker,   G. Van Meurs,   H. Balner,  

 

期刊: Tissue Antigens  (WILEY Available online 1982)
卷期: Volume 19, issue 1  

页码: 69-78

 

ISSN:0001-2815

 

年代: 1982

 

DOI:10.1111/j.1399-0039.1982.tb01417.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

A population of 94 unrelated rhesus monkeys was typed for MLC antigens using 38 homozygous typing cells which define ten RhLA—D specificities. A genetic analysis showed that the ten D specificities are alleles of a single locus, the gene frequencies of which are in Hardy‐Weinberg equilibrium. The association between the cellularly defined D and the serologically defined DR antigens in the population was usually high, confirming the close relationship between D and DR antigens. Two new associations were found, i.e. between the D‐locus antigens 9 and 10 and the serologically defined B‐cell antigens 109 and 101, respectively. This observation confirms prior speculations that the latter two antigens may belong to the DR

 

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