Automated Two-Stage Assay for Determination of Antithrombin III with a Centrifugal Analyzer
作者:
Thorkild Andreasen,
期刊:
Pathophysiology of Haemostasis and Thrombosis
(Karger Available online 1980)
卷期:
Volume 9,
issue 2
页码: 65-70
ISSN:1424-8832
年代: 1980
DOI:10.1159/000214342
出版商: S. Karger AG
关键词: Myocardial infarction;Deep-vein thrombosis;Antithrombin III;Centrifugal analyzer;Chromogenic substrate
数据来源: Karger
摘要:
The thrombin-inactivating α2-globulin, antithrombin III (At-III), was measured in plasma and urine with a chromogenic tripeptide substrate, using a centrifugal analyzer. Plasma At-III was subnormal in liver disease. In acute myocardial infarction a mean At-III of approximately 120% of normal was found. At-III in persons who developed deep-vein thrombosis decreased significantly (p < 0.05) between the day of admission and the 3rd day after admission to hospital. Urine from normals did not contain detectable At-III. With increasing urinary albumin increasing concentration of At-III was found
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