This study examined the possible mediating effects of hardiness and Type A behavior on the relationship between stressful life events and physical and psychological well-being in a Japanese male sample (N= 78). The ANOVA showed the main effects of hardiness on both physical symptoms and depression. It is indicated that hardiness protects individuals from both physical symptoms and depression. There was a significant stressful life events × Type A interaction, indicating that the Type As tended to possess physical symptoms even when stressful life events decreased. No three-way interaction among hardiness, Type A behavior, and stressful life events was found. The results suggested that hardiness and Type A were independently related to physical and psychological well-being. Implications for the influence of Japanese culture on hardiness and Type A behavior are discussed.