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Surveillance of Down’s Syndrome as a Paradigm of Population Monitoring

 

作者: N.E. Morton,   J. Lindsten,  

 

期刊: Human Heredity  （Karger Available online 1976）
卷期: Volume 26, issue 5  

页码: 360-371

 

ISSN:0001-5652

 

年代: 1976

 

DOI:10.1159/000152828

 

出版商: S. Karger AG

 

关键词: Down’s syndrome;Surveillance;Mutagenicity tests;Incidence variations

 

数据来源: Karger

 

摘要:

Principles of sequential and supplementary tests for an increased frequency of a sentinel phenotype are illustrated by Australian and Swedish data on Down’s syndrome. Sequential analysis offers substantial advantages over fixed sample size theory for monitoring teratogenic and other noxious agent

 

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