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Clearance and Disposition of Urea in the Perfused Human Placenta

 

作者: M. Nandakumaran,   R. Kasrawi,   M. Al-Bustari,   N. El-Tomi,   H. Hathout,  

 

期刊: Medical Principles and Practice  （Karger Available online 1989）
卷期: Volume 1, issue 1  

页码: 52-57

 

ISSN:1011-7571

 

年代: 1989

 

DOI:10.1159/000157280

 

出版商: S. Karger AG

 

关键词: Urea clearance;Human placenta;Lobular perfusion;In vitro

 

数据来源: Karger

 

摘要:

Urea clearance and disposition is studied in perfused human placenta in vitro using a novel perfusion technique of isolated placental lobules. The results on urea clearance compare well with published reports. The study shows the suitability of urea as a reference marker in placental perfusion studies. It is concluded that urea could serve as an effective reference marker in preference to antipyrine in clearance studies of molecules with membrane-limited transfer.

 

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