A Status Report – Human Prostatic Carcinoma, with Emphasis on Potential for Viral Etiology
作者:
R.F. Zeigel,
S.K. Arya,
J.S. Horoszewicz,
W.A. Carter,
期刊:
Oncology
(Karger Available online 1977)
卷期:
Volume 34,
issue 1
页码: 29-44
ISSN:0030-2414
年代: 1977
DOI:10.1159/000225177
出版商: S. Karger AG
关键词: Prostatic cancer;Possible viral etiology;Clinical staging;Treatment;Prognosis;Morphology;Pathology;Enzymology;Immunology;Hormonal studies
数据来源: Karger
摘要:
Several parameters of the biology of cancer of the prostate have been reviewed with a continuing assessment of the possible etiologic role of virus. These aspects include epidemiology, clinical studies, morphology, pathology, enzymology, immunology, endocrinology, model animal studies, in vitro systems, and viral investigations. From available literature it is concluded that, to date, the association with several urogenital tissues of herpes-type viruses has been best documented. It is suggested that a fundamental barrier to more sophisticated virologic and biologic studies is the lack of long term cell cultures of normal and pathologic prostate epithelium from males of all ages.
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