Autopsy Findings of Nonacid-Fast Bacteria in Scleroderma
作者:
Alan R. Cantwell, Jr.,
Dan W. Kelso,
期刊:
Dermatology
(Karger Available online 1980)
卷期:
Volume 160,
issue 2
页码: 90-99
ISSN:1018-8665
年代: 1980
DOI:10.1159/000250479
出版商: S. Karger AG
关键词: progressive systemic;Mycobacteria;nonacid-fast;Bacteria;cell wall deficient;Bacteria;pleomorphic;L forms;Sclerobacillus;Autopsy findings;Bacteriologic findings;Histopathologic findings;generalized;Sclerosis;Scleroderma
数据来源: Karger
摘要:
Microscopic tissue sections stained for bacteria were studied from autopsy material from a fatal case of scleroderma (progressive systemic sclerosis). Extra- and intracellular, variable-sized, pleomorphic but predominantly coccoid bacteria were observed in some organs such as in heart, lungs, adrenals, kidneys, pancreas, skin, and in the connective tissue. An attempt is made to correlate the ante-mortem skin culture material with the post-mortem histopathologic finding of bacteria. It is hypothesized that these microbes observed in tissue might represent in vivo, cell wall deficient L forms, which may be implicated in the pathogenesis of scleroderma.
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