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Effect of an R Plasmid on the Virulence of a Hospital Strain ofEscherichia coli

 

作者: Jacques Michel,   Jacqueline Miller,   Theodore Sacks,  

 

期刊: Chemotherapy  （Karger Available online 1980）
卷期: Volume 26, issue 6  

页码: 427-430

 

ISSN:0009-3157

 

年代: 1980

 

DOI:10.1159/000237938

 

出版商: S. Karger AG

 

关键词: R plasmid;Escherichia coli;Virulence

 

数据来源: Karger

 

摘要:

The virulence of a multiple antibiotic-resistant isolate of Escherichia coli was compared to that of the same isolate ‘cured’ of its resistance by acridine orange, and to that of the cured bacteria transformed back to resistance by the plasmid DNA extracted from the original resistant isolate. There were virtually no differences in the mouse LD 50 of these three variants of the same organ

 

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