This article explores the efficiency of automated literature search techniques to facilitate literature accessibility. It presents three related studies using the National Library of Medicine (NLM) literature search on nurse practitioners (1980) as the point of reference. The studies investigate three questions: Is the search reproducible, does it locate the most important articles pertaining to nurse practitioner effectiveness, and can a system be developed to decide efficiently which articles in a voluminous search output should actually be obtained? Results indicate that the NLM search is reproducible but that it lists only a small proportion of available studies. Neither the NLM document nor a computer search using the parameters it cites located a high proportion of critically nominated studies. However, based upon classification of their titles, a workable system can be developed to identify those articles in a search output that are relevant and should be retrieved.