AbstractIn order to examine the total syntheses of ochotensine (1) and ochotensimine (II), one of the isomers, iso‐ochotensine (III), was synthesized as a preliminary experiment. Namely, Wittig reaction of VI, followed by treatment with sodium bicarbonate solution, gave the expected compound, 7‐ethoxycarbonyl‐3‐ethoxycarbonyloxy‐2‐methoxy‐13‐methyIene‐10,11‐methyIene‐dioxyochotensinan (VII) which was reduced with lithium aluminum hydride to give III. This was also obtained by methylation of 3‐hydroxy‐2‐methoxy‐13‐methylene‐10,11