Comparison of Lung Volume Measurements by Single Breath Helium and Multiple Breath Nitrogen Equilibration Methods in Normal Subjects and COPD Patients
作者:
Thomas M. Brugman,
James F. Morris,
William P. Temple,
期刊:
Respiration
(Karger Available online 1986)
卷期:
Volume 49,
issue 1
页码: 52-60
ISSN:0025-7931
年代: 1986
DOI:10.1159/000194859
出版商: S. Karger AG
关键词: Measurements;lung volume;Total lung capacity;Lung capacities;Functional residual capacity
数据来源: Karger
摘要:
The validity of the single breath helium dilution method for accurate measurement of the total lung capacity (TLC) was investigated. Comparison was made with the multiple breath nitrogen equilibration technique in 22 normal subjects and 37 patients with chronic obstructive pulmonary disease (COPD). The single breath method underestimated the TLC in all the normal individuals and 33 of 37 patients with COPD. Possible explanations for the falsely low lung volumes include uneven distribution of inspired air due to closing volumes and induced bronchoconstriction.
点击下载:
PDF
(1286KB)
返 回